0

Doxofylline

Doxofylline
Doxofylline
Price And Quantity
  • Kilograms/Kilograms
  • 10
  • Kilograms/Kilograms
  • 1900 INR
  • 1800.00 - 1900.00 INR
Product Specifications
  • Medicine Raw Materials
  • Medicine Raw Materials
  • Powder
  • ACTIVE PHARMACEUTICAL INGREDIEANT
  • Powder
  • Anti-Bacterial
  • Other
  • TABLETS AND CAPSULES
  • TABLETS AND CAPSULES
  • Suitable For All
  • TABLETS AND CAPSULES
  • 2000 KG Unit
  • Doxofylline is mainly comes in crystalline form so store in a cool and dry place. Do not store in moistly or wet place like bathroom or kitchen.
Product Description

Niksan Pharmaceutical is words top leading manufacturer, exporter,trader and supplier of Doxofylline APIas well as finished pharmaceutical products of Doxofylline among the pharmaceutical companies. Our productDoxofylline is widely used and appreciated by our group companies and also ourcustomers and users all around the nations. We offer the Doxofylline in veryaffordable price.

 

Niksan Pharmaceutical and Niksangroup companies are the very well-known manufacturers, suppliers anddistributors of Doxofylline products.

 

Niksan Pharmaceutical are manufacturing and exporting very largequantity of Doxofylline in countrieslike Philippines, Bangladesh, Nepal, Pakistan, Thailand, United states, Paraguay,Argentina, Dominican Republic, Sudan, Hong Kong, Seychelles, Algeria, Iran,Bulgaria, Lithuania, Poland, Sri Lanka, Romania, Uruguay, Serbia, New Zealand,Sweden, Hungary, Mauritius, Vanuatu, Malta, Kazakistan, Slovenia, Bolivia,Japan, Russia, Afghanistan, Latvia, Lithuania, United Arab Emirates,Seychelles, Peru, Switzerland, Tunisia, France, Chile, South Korea, United Kingdom,Australia, Greece, Austria and Germany.

 

Doxofylline is one type of anti-asthmatic drug. Doxofyllineis belongs to the Bronchodilator type of medicine. Mainly Doxofylline is widelyused in a treatment of chronic obstructive pulmonary disease (COPD) and also used to treatasthma.

Doxofylline is also called xanthenes derivative drugwhich is used in breathing problems. We can say that Doxofylline makesbreathing easier.

Doxofylline acts as a posphodiesterase inhibitorwhich can use in bronchospasm and other respiratory disorders.

 

SYNONYMS:  Doxofilina,Doxofylline, Doxophylline. 

 

IUPACNAME: 7-[(1, 3-dioxolan-2-yl) methyl]-1, 3-dimethyl-2, 3,6, 7-tetrahydro-1H-purine-2, 6-Dione

 

CAS NO: 69975-86-6

 

FORMULA: C11H14N4O4

 

MOLECULAR MASS: 266.25 g/mol

 

STORAGE: Doxofylline is mainly comes in crystalline form sostore in a cool and dry place. Do not store in moistly or wet place likebathroom or kitchen. Keep the medicine away from reach of children and pets. Storethe medication as directed by your doctor.

 

APPLICATION OF DOXOFYLLINE: Doxofyllineis an antitussive medicine which is mostly used in a treatment of asthma andother respiratory problems. Doxofylline shows fewer side effect then the otherxanthine type of medicine, that’s why Doxofylline chosen over the otherxanthine class drug.

 

HOW TO USE: Doxofylline comes in two dosage forms oneis Tablet and Syrup. Simply take Doxofylline tablet or syrup by mouth (orally)with food or without food. The prescribed dose of Doxofylline must be1200mg perday. Try to take medicine at a same time every day for the better improvement.

 

HOW DOXOFYLLINE WORKS: The main mechanism of action ofDoxofylline is not well known but we can say that theDoxofylline works byinhibiting the posphodiesterase activity, by this process the cAMP level raisesand by this the smooth muscle relaxation occurs.

 

CONTRAINDICATIONS OF DOXOFYLLINE: If youhave hypersensitivity kindly avoid Doxofylline and chose alternative medicine. Kindlyavoid the Doxofylline medication if you have any liver or kidney related problemsor if you have any hypoxemia (low O2 level inblood) or have any cardiac arrhythmias. Before the writing of prescription tellyour doctor if you have history of peptic ulcer or hyperthyroidism.

 

PHARMACOKINETICS OF DOXOFYLLINE:Doxofylline working very differently in the body by that after taking of theregular dose Doxofylline reaches in steady state in about 4 days. The absolutebio availability of Doxofylline is 63±25%. Basically methylxanthines aredistributed into all over body compartment. The residues of Doxofyllineare found in breast milk also. Doxofylline undergoes hepatic metabolism inwhich 90% of the drug clears from the body. Doxofylline is orally administereddrug is only 4% excreted by the urination, the remaining drug will excreted infaces.

 

SIDE EFFECTS OF DOXOFYLLINE: Therewere very less side effects of Doxofylline are noticed, most of them are verycommon side effects like nausea, vomiting, headache, obsess with food oranorexia. There are other side effects of Doxofylline like heart burn,dyspepsia are the notable side effects.

 

PRECAUTIONS OF DOXOFYLLINE: Tell your doctor ifyou have any history of peptic ulcer or hyperthyroidism. Kindly do not takeDoxofylline if you have any liver or kidney problem.

 

CDSCO APPROVAL: Doxofylline tablet (20mg and 400mg)tablets are approved by CDSCO in India in 31.08.2005.

Doxofyllinesyrup (20mg/ml) is approved by CDSCO in India in 31.08.2005.

Doxofylline Syrup (20mg/ml) is approved by CDSCO in India in30.03.2006.

Doxofylline Tablet (400mg) is approved by CDSCO in India in08.02.2006.

Doxofylline ER tablets (400mg/800mg) areapproved by CDSCO in India in 12.03.2008.

Doxofylline 400 mg + Ambroxol 30 mg Tablets are approved by CDSCOin India in 23.12.2009.

Doxofylline MR Tablet (650mg) is approved by CDSCO in India in11.03.2010.

 

FORMULATION OF DOXOFYLLINE AVAILABLEIN MARKET:

Doxofyllinetablets 20mg

Doxofyllinetablets 400 mg

Doxofyllinesyrup 20mg/ml

Doxofylline ER tablets 400mg

Doxofylline ER tablets 800mg

Doxofylline 400 mg + Ambroxol 30 mg tablets

Doxofylline MR Tablets 650mg

 

Note: Product protected by validpatents are not offered for sale in countries where such patents are stillvalid and its liability is at Buyers Risk

 

REFERENCES:

 

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult

Trade Information
  • SAHAR AIR CARGO
  • Cheque, Western Union, Cash Against Delivery (CAD), Paypal, Cash Advance (CA), Days after Acceptance (DA), Telegraphic Transfer (T/T), Letter of Credit at Sight (Sight L/C), Letter of Credit (L/C), Delivery Point (DP), Cash in Advance (CID), Cash on Delivery (COD)
  • 7 Days
  • Yes
  • Free samples are available
  • Double LDPE Liners in HDPE carboys
  • Africa, Middle East, Western Europe, Eastern Europe, South America, North America, Central America, Australia, Asia
  • All India
  • FDCA, GMP, GLP AND ISO
Contact Us

Plot No. 4706/03, Gidc Estate, SF-12, Shrinathji Arcade, Near Meghmani Chowkadi, Ankleshwar, Gujarat, 393002, India